Peyronie's (pay-roe-NEEZ) disease is a condition in which fibrous scar tissue forms in the deeper tissues under the skin of the penis. This causes curved, painful erections. It also can make the penis shorter while erect. Peyronie's disease is not caused by cancer. Penises vary in shape and size. Peyronie's disease (PD) is an acquired, localized fibrotic disorder of the tunica albuginea, resulting in penile deformity; mass; pain; and, in some men, erectile dysfunction. Peyronie's disease occurs when a buildup of scar tissue causes curved and often painful erections. Learn the symptoms, causes, and treatment options. Learn about Peyronie’s disease, its causes, symptoms, and treatment options including medication, injections, and surgery. Peyronie’s disease is a connective tissue disorder of the penis that can be likened to Dupuytren’s contracture of the hand. It is characterized by the triad of bent erections, pain in the penis with erections and palpable penile plaque. Peyronie's disease (PD) is a benign, acquired penile connective tissue disease characterized by the occurrence of fibrotic plaques within the tunica albuginea — the dense elastic covering of the corpora cavernosa. Peyronie’s disease is a condition in which scar tissue causes your penis to curve or lose length or girth. In some cases, it can cause pain and make it difficult or impossible for you to have sex. Peyronie's disease causes your penis to curve due to plaque build-up under your skin. You can treat this condition with injections, oral medications, and, in severe cases, surgery. Learn about Peyronie’s disease, the causes, how it develops, the risk factors, diagnosis, and treatment options, and clinical trials. Peyronie's disease is a condition in which scar tissue in the penis causes the penis to bend. WebMD looks at its causes, symptoms, and treatment.